Metastatic Mineralization

Etiology:  The cause of metastatic mineralization is not known, but may be due to an inappropriate dietary mineral balance [1].

Incidence:  Metastatic mineralization is infrequently seen in guinea pigs over one year of age.

Clinical Signs:  Clinical signs are non-specific and may include alopecia, muscle stiffness and unthriftiness.

Pathology:  Mineral deposits accumulate most commonly within the kidney (A), but can also be seen within the smooth muscle of the vasculature and GI tract, periarticular soft tissues, liver and heart (B).

Diagnosis:  Mineralization of smooth muscle and kidney tissues are seen on histology.

 

 

 

 

 

 

1.            The Laboratory Rabbit, Guinea Pig, Hamster, And Other Rodents. 1 ed2012, 225 Wyman Street, Waltham, MA 02451: Elsevier.