Etiology: The pathogenesis of pregnancy toxemia is not well-known, but may be similar to ketosis in sheep. Predisposing factors include breed, age, sex, obesity, and the number of previous litters.
Incidence: Pregnancy toxemia is seldom recognized in domestic rabbits .
Clinical Signs: Signs range from a mild, nearly asymptomatic condition to a severe, rapidly fatal disease. The most common signs are depression, dyspnea, an acetic (vinegar-like) odor to the breath, decreased urine production, abortion, CNS signs, and sudden death just prior to or just after kindling.
Pathology: Gross lesions include general obesity, areas of necrosis in the mesenteric fat, and a pale yellow liver, heart, and kidneys. Fatty changes are seen microscopically in the liver, heart, and kidneys.
Diagnosis: The diagnosis is based on history and clinical signs.
1. The Laboratory Rabbit, Guinea Pig, Hamster, And Other Rodents. 1 ed2012, 225 Wyman Street, Waltham, MA 02451: Elsevier.